Synthesis, characterization, and biological activities of copper(II), zinc(II), iron(III), cobalt(III), and nickel(II) complexes of D-glucosamine

Cu(II), Zn(II), Fe(III), Co(III), and NI(II) complexes of D-glucosamine (Gl uH(2). HCl) were synthesized. These complexes, Cu (II)(GluH)(OAc)(H2O).H2O (1), Zn(II)(GluH)(OAc)(H2O).H2O (2), Fe(III)(Glu)(OAc)(H2O).H2O (3), Co(III )(Glu)(OAc)(H2O).H2O (4), and Ni(II)(GluH)(OAc)(H2O).H2O (5), were characte rized by elemental analyses, conductivity and magnetic susceptibility measu rements, and infrared and electronic spectra. Cu(II)(GluH) (OAc)(H2O).H2O w as further characterized by ESR. The ligand (GluH(2). HCl) and Zn(II) (GluH )(OAc)(H2O).H2O were also characterized by H-1 NMR and C-13 NMR. It is sugg ested that all of the complexes have pseudo-tetrahedral structures and are nonelectrolytes. These complexes are superoxide free radical (O-2(.-)) scav engers.