A facile synthesis of N-aryl aziridines

Authors
Sriraghavan, K Ramakrishnan, VT
Citation
K. Sriraghavan et Vt. Ramakrishnan, A facile synthesis of N-aryl aziridines, SYN COMMUN, 31(7), 2001, pp. 1105-1121
Citations number
34
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
7
Year of publication
2001
Pages
1105 - 1121
Database
ISI
SICI code
0039-7911(2001)31:7<1105:AFSONA>2.0.ZU;2-F
Abstract
Reaction of N-aryl-beta -amino alcohols with p-toluenesulphonyl chloride un der phase transfer catalytic condition gave the corresponding N-aryl azirid ines in good yields, whereas N-alkyl-beta -amino alcohol [for e.g., L-ephed rine] gave the corresponding N-tosyl derivative as the major product, along with the expected N-alkyl aziridines in lower yield.