Sk. Bertilsson et al., The aza-Diels-Alder reaction protocol - a useful approach to chiral, sterically constrained alpha-amino acid derivatives, TETRAHEDRON, 57(30), 2001, pp. 6399-6406
Different types of polycyclic alpha -amino acid derivatives are prepared fr
om chiral imines by using well-established aza-Diels-Alder reaction conditi
ons. Simply by varying the diene moiety, different products such as spirocy
clic compounds 8 and 9, anthracene 10, and tetrahydroquinolines 15-21 are f
ormed. (C) 2001 Elsevier Science Ltd. All rights reserved.