Workshop studies on monoclonal antibodies in the myeloid panel with CD11 specificity

Authors
Dominguez, J Alvarez, B Alonso, F Thacker, E Haverson, K McCullough, K Summerfield, A Ezquerra, A
Citation
J. Dominguez et al., Workshop studies on monoclonal antibodies in the myeloid panel with CD11 specificity, VET IMMUNOL, 80(1-2), 2001, pp. 111-119
Citations number
8
Categorie Soggetti
Veterinary Medicine/Animal Health",Immunology
Journal title
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
ISSN journal
01652427 → ACNP
Volume
80
Issue
1-2
Year of publication
2001
Pages
111 - 119
Database
ISI
SICI code
0165-2427(20010720)80:1-2<111:WSOMAI>2.0.ZU;2-O
Abstract
Several putative anti-human and swine CD11-specific monoclonal antibodies ( mAbs) were included in the myeloid section of the Third International Swine CD Workshop. Failure of clustering analysis to group these mAbs together p rompted additional analyses to define the specificities of these m-Ab. Comb ination of one and two-color flow cytometry (FCM) and immunoprecipitation ( IP) allowed the definition of the mAb into three CD11 groups. Cellular dist ribution of the molecules recognized by anti-human CD I lb and c mAbs on sw ine cells proved to be significantly different from that found in humans. ( C) 2001 Published by Elsevier Science B.V.