Electron-beam computed tomography (EBCT) and nuclear cardiology techniques
are both valuable in the noninvasive assessment of patients with suspected
coronary artery disease. The techniques, however, are different in the info
rmation they provide about the patient. EBCT provides anatomic information
on coronary atherosclerosis, whereas myocardial perfusion single-photon emi
ssion computed tomography assesses the physiologic significance of coronary
stenosis. Because of these differences, the techniques are highly compleme
ntary.
In considering the complementary nature of these methods, it is important t
o clarify the issues being raised. An important question in the considerati
on of a patient with known or suspected coronary artery disease is, What is
the risk in an individual patient of developing clinical coronary artery d
isease? The answer to this question will determine who needs aggressive med
ical management. A second question in a suspected coronary artery disease p
atient is, What is the risk of cardiac death? As will be discussed, this ri
sk, in general, determines the need to consider coronary revascularization.
In the former question, EBCT testing and clinical assessment alone is usua
lly sufficient, and in some cases nuclear testing can be of additional valu
e. In answering the second question, on the basis of currently available da
ta, the EBCT and nuclear cardiology studies appear to be operating in a com
plementary fashion. (C) 2001 by Excerpta Medico, Inc.