Preliminary study of altered skin temperature at body sites associated with self-injurious behavior in adults who have developmental disabilities

In this study, the sensory status of 4 nonverbal adults with mental retarda tion and severe self-injury was examined using skin temperature measures pr ior to opiate antagonist treatment. Double-blind, placebo-controlled, exper imental ABAB designs were used to evaluate the effects of naltrexone hydroc hloride (1.5 mg/kg/day). For each participant, the body site targeted most frequently for self-injury was associated with altered skin temperature and reduced by naltrexone. In all cases, neither infrequent self-injury body s ites nor non-self-injury body sites were associated with altered skin tempe rature. Further controlled studies are warranted to examine the value of as sessing pain status and skin temperature in nonverbal patients with mental retardation and related developmental disabilities who present with tissue- damaging SIB.