Development of control serum for microbial antibody tests

Authors
Uemura, Y Baba, T Hasegawa, Y Yanagihara, O Matsumoto, K Kawai, T
Citation
Y. Uemura et al., Development of control serum for microbial antibody tests, BIOLOGICALS, 29(1), 2001, pp. 39-43
Citations number
26
Categorie Soggetti
Microbiology
Journal title
BIOLOGICALS
ISSN journal
10451056 → ACNP
Volume
29
Issue
1
Year of publication
2001
Pages
39 - 43
Database
ISI
SICI code
1045-1056(200103)29:1<39:DOCSFM>2.0.ZU;2-U
Abstract
Control sera are an essential component of in-vitro clinical diagnostic rea gents. We have developed a control serum for HBsAg, anti-HCV, anti-HIV and anti-Treponema pallidum testing. Since this control serum is prepared from human plasma, we paid special attention to viral safety. We incorporated th ree viral inactivation methods into the manufacturing process that maintain the necessary characteristics of a stable control serum. (C) 2001 The Inte rnational Association for Biologicals.