Electrochemical study of amoxicillin antibiotic across liquid-liquid interface

Citation
L. Basaez et al., Electrochemical study of amoxicillin antibiotic across liquid-liquid interface, BOL SOC CH, 46(2), 2001, pp. 203-208
Citations number
13
Categorie Soggetti
Chemistry
Journal title
BOLETIN DE LA SOCIEDAD CHILENA DE QUIMICA
ISSN journal
03661644 → ACNP
Volume
46
Issue
2
Year of publication
2001
Pages
203 - 208
Database
ISI
SICI code
0366-1644(200106)46:2<203:ESOAAA>2.0.ZU;2-Q
Abstract
Many molecules of farmacological interest could not have been studied for t he classical electrochemical technical due to the great complexity that the y present when they are submitted to voltammetric processes. An electrochem ical method for quantifying betalactam antibiotic (amoxicillin) is describe d. Cyclic voltammetry at the water/nitrobenzene interface in a four-electro de system is used. The zwitterion compound was ionized to the necessary ele ctrochemical form by pH adjustment. The ionized antibiotic is studied by vo ltammetric transfer since water to nitrobenzene using the method of the int erface between two immiscible electrolyte solutions (ITIES).