New mammographic stromal deformity: what is the significance of this finding on screening mammograms?

Current practice within the NHS Breast Screening Programme recommends surgi cal excision of screen detected areas of stromal deformity as differentiati ng carcinomas from radial scars and excluding in situ malignancy in associa tion with radial scars is unreliable. We retrospectively reviewed all cases recalled for assessment over a 4 year period, identified to have an area o f persistent stromal deformity not associated with surgical scarring and wi thout an associated mammographic mass. Thirty women were prevalent (first) round screens - 17 cases proved to be malignant and 13 benign. The latter g roup included three cases of atypical ductal hyperplasia. Nineteen women we re incident (subsequent) round screens - all 19 cases proved to be malignan t. This study supports the practice of surgically removing all areas of str omal deformity, particularly new areas of stromal deformity detected in the incident round, as in this group the likelihood of malignancy is extremely high. (C) 2001 Harcourt Publishers Ltd.