Rg. Johnson et al., PREDICTORS OF CABG WITHIN ONE-YEAR OF SUCCESSFUL PTCA - A RETROSPECTIVE, CASE-CONTROL STUDY, The Annals of thoracic surgery, 64(1), 1997, pp. 3-8
Background. We previously have established characteristics predictive
of the need for coronary artery bypass grafting (CABG) over many years
after successful percutaneous transluminal coronary angioplasty (PTCA
). In this study, we examined the factors associated with the need for
CABG within 1 year of successful PTCA, and the recent impact of newer
, catheter-based technologies. Methods. From January 1982 through Dece
mber 1995, 234 patients underwent CABG within 1 year of a successful '
'index'' PTCA at our hospital. Emergency operations within 12 hours of
index PTCA were excluded. These cases were matched with 234 controls
who underwent a successful index PTCA but did not require a subsequent
CABG during the next year. Cases were matched by the date of their in
dex PTCA, and 1-year follow-up was complete for all patients. Results.
Before index PTCA there were no differences between the groups in ter
ms of age, sex, diabetes, prior myocardial infarction, ejection fracti
on, duration of anginal symptoms, hypertension, hyperlipidemia, family
history, or obesity (all nonsignificant). At index PTCA the cases had
a greater mean number of lesions measuring 70% or greater compared wi
th the controls (2.8 versus 1.8, respectively; p < 0.0001). The cases
were more likely to have critical (70% or greater) proximal left anter
ior descending artery, proximal first obtuse marginal artery, and righ
t posterior descending artery stenoses. The use of stents or atherecto
my devices was not significantly more common among the controls (21% o
f controls versus 17.1% of cases; p = 0.35). Complete revascularizatio
n was achieved in significantly fewer of the cases than the controls (
91 versus 156, respectively; p < 0.0001). The cases underwent CABG at
a mean of 3 months (86% within 6 months) after PTCA. Among those who h
ad a diagnostic catheterization, 52% of the patients had both restenos
is of a dilated lesion and progression of other disease. Only 5 of 75
patients who had restenosis of a dilated lesion had a stent or an athe
rectomy device used at index PTCA. Of note, 13% (30 of 234) required a
n emergency operation, with an overall operative mortality rate of 3%
(7 of 234). Conclusions. Although the likelihood of local restenosis i
s decreased by newer interventional techniques, the need for CABG with
in 1 year after successful PTCA is not diminished. The number of criti
cal lesions and their location are the best predictors of the need for
early CABG. If early post-PTCA CABG is to be avoided, patients who ca
nnot be completely revascularized by PTCA should be revascularized by
CABG. (C) 1997 by The Society of Thoracic Surgeons.