W. Burger et al., SUCCESSFUL THROMBOLYSIS AFTER PROSTHETIC PULMONARY VALVE OBSTRUCTION UNDER ASPIRIN MONOTHERAPY, The Annals of thoracic surgery, 64(1), 1997, pp. 255-257
In a 22-year-old woman with recent onset of left-sided chest pain and
exertional dyspnea, echocardiography revealed obstruction of a St. Jud
e Medical bileaflet prosthetic valve (size 23 mm) in the pulmonary pos
ition. Oral anticoagulation had been replaced for the previous 7 years
by aspirin as the sole antithrombotic treatment. The valve had been i
nserted 16 years ago for pulmonary atresia. Valve function was restore
d by systemic application of 9 million units of urokinase.