Catalyzed asymmetric dialkylzinc addition to benzaldehyde in the presence of new chiral ligands - delta-(1-phenethyl)aminoalcohols

Authors
Demyanovich, VM Shishkina, IN Zefirov, NS
Citation
Vm. Demyanovich et al., Catalyzed asymmetric dialkylzinc addition to benzaldehyde in the presence of new chiral ligands - delta-(1-phenethyl)aminoalcohols, CHIRALITY, 13(8), 2001, pp. 507-509
Citations number
10
Categorie Soggetti
Chemistry & Analysis
Journal title
CHIRALITY
ISSN journal
08990042 → ACNP
Volume
13
Issue
8
Year of publication
2001
Pages
507 - 509
Database
ISI
SICI code
0899-0042(200108)13:8<507:CADATB>2.0.ZU;2-B
Abstract
A series of delta -aminoalcohols prepared from (S)- and (R)-N,N-dimethyl-1- phenethylamines was found to catalyze the enantio selective addition of die thylzinc to benzaldehyde to yield optically active 1-phenylpropanol with en antiomeric excess 60-85%. (C) 2001 Wiley-Liss, Inc.