To establish the natural progress pattern of postoperative bone uptake, a p
eriprosthetic quantitative technetium-99m methylene diphosphonate scintisca
n was done on 80 asymptomatic hips (62 patients) with uncomplicated cementl
ess hydroxyapatite-coated total hip arthroplasties and 20 healthy control h
ips (10 subjects) without previous surgery. The patients were studied in ei
ght groups at scheduled intervals of 1 to 48 months. There were 10 hips in
each group. The measurement of bone uptake in the healthy untreated control
group indicated that the uptake ratio in the proximal femur was physiologi
cally higher in the metaphyseal area than in the diaphyseal area and the up
take ratio in the acetabulum. appeared to be much higher than that of the p
roximal femur. In the patient group, the uptake ratio around the femoral st
em area and the acetabular cup area showed a statistically significant decr
ease between 1 and 3 months after surgery and changed little after 3 months
. Comparing the result of the patient group with that of the healthy untrea
ted control group, the uptake ratio decreased much faster in the hydroxyapa
tite-coated metaphyseal zone than in the noncoated diaphyseal zone of the f
emoral stem area. In the acetabular cup area, the uptake ratio decreased fa
st, as in the hydroxyapatite-coated metaphyseal zone of the femoral stem ar
ea. Based on these clinical results, a quantitative bone scan may be a help
ful diagnostic procedure for evaluating postoperative progress when used in
conjunction with clinical symptoms and radiologic examinations.