ISOLATION OF HTLV-1 FROM AN AGGRESSIVE FORM OF ATL IN A ROMANIAN PATIENT NOT AT RISK OF INFECTION AND WITH SERONEGATIVE FAMILY MEMBERS

Authors
MANCA N FERREMI P DESIMONE N PIRALI F TURANO A
Citation
N. Manca et al., ISOLATION OF HTLV-1 FROM AN AGGRESSIVE FORM OF ATL IN A ROMANIAN PATIENT NOT AT RISK OF INFECTION AND WITH SERONEGATIVE FAMILY MEMBERS, The New microbiologica, 20(3), 1997, pp. 177-185
Citations number
29
Categorie Soggetti
Microbiology
Journal title
The New microbiologica
ISSN journal
11217138 → ACNP
Volume
20
Issue
3
Year of publication
1997
Pages
177 - 185
Database
ISI
SICI code
1121-7138(1997)20:3<177:IOHFAA>2.0.ZU;2-P
Abstract
We present the clinical, virological and haematochemical data of a 22 year old patient from Romania with Adult T Cell Leukaemia (ATL). Viral isolation in peripheral mononuclear blood cells (PMBC), detection of DNA sequences of HTLV-1 by Polymerase Chain Reaction (PCR) and of anti bodies by Elisa and Western blot were performed. The patient does not belong to any risk group and additionally all members of her family ar e seronegative for HTLV-1, the aetiological agent of ATL. The role of viral infection remains open.