Second-trimester biochemical screening

Authors
Evans, MI O'Brien, JE Dvorin, E Harrison, H Bui, TH
Citation
Mi. Evans et al., Second-trimester biochemical screening, CLIN PERIN, 28(2), 2001, pp. 289
Citations number
61
Categorie Soggetti
Reproductive Medicine
Journal title
CLINICS IN PERINATOLOGY
ISSN journal
00955108 → ACNP
Volume
28
Issue
2
Year of publication
2001
Database
ISI
SICI code
0095-5108(200106)28:2<289:SBS>2.0.ZU;2-S
Abstract
-Biochemical screening for neural tube defects and chromosome abnormalities , particularly Down syndrome, has developed over the past 30 years and has become a mainstay of obstetric screening. Recent advances have improved the sensitivity of Down syndrome screening to approximately 65%, but much cont roversy remains as to the best approaches for further improvement.