The mercury-based vaccine preservative thiomersal has come under scrutiny i
n recent months because of its presence in certain vaccines that provide th
e foundation of childhood immunisation schedules. Over the past decade new
vaccines have been added to the recommended childhood schedule, and the rel
atively smaller bodyweight of infants has led to concern that the cumulativ
e exposure of mercury from infant vaccines may exceed certain guidelines fo
r the human consumption of mercury. In the US, government agencies and prof
essional societies have recently recommended that thiomersal be removed alt
ogether from vaccines. Some involved in developing vaccine policy feel that
the evidence to support these safety concerns has not risen to the level r
equired for such a response. This apparent divergence of opinion has left h
ealthcare professionals and the public with uncertainty about the potential
health effects from low level exposure to thiomersal as well as the necess
ity of removing thiomersal from vaccines. At present, scientific investigat
ion has not found conclusive evidence of harm from thiomersal in vaccines.
As a precautionary measure, efforts are under way to remove or replace thio
mersal from vaccines and providers should anticipate the availability of mo
re vaccine products that are thiomersal-free over the coming years.