In North Carolina, we analyzed cumulative data for tuberculosis (TB) from 1
980 through 1999 to determine trends in incidence, population subgroups at
risk, and implications for health policy-makers. The overall incidence rate
s declined significantly over the study period (p = 0.0001). This decline c
orrelates strongly with an increase in TB patients receiving directly obser
ved therapy. Males have approximately twice the risk for disease, and perso
ns > 65 years of age are at the highest risk. For every Caucasian with TB,
six blacks, six Hispanics, and eight Asians have the disease. TB incidence
rates are declining in all other population subgroups but increasing in for
eign-born and Hispanic persons.