Bioassays with the marine amphipod Corophium volutator were performed simul
taneously in situ and in the laboratory using sediments sampled from the in
situ locations. In most cases, the in situ response was significantly high
er compared to the laboratory response. This difference was not caused by d
irect influence of the use of the field chamber on Corophium sp., nor was t
he difference caused by the overlying water used. Experiments showed homoge
nization can affect the toxicity of a sediment, but not in such a way that
it can completely explain the difference between the response in situ and i
n the laboratory. Possible explanatory factors are harbor activity, storms,
and temperature. To reduce the influence of some of these factors, the bes
t period of the year to perform in situ bioassays with C. volutator is May,
June, or September.