Lymphoma-like lesion of the uterine cervix is a benign reactive lymphoid hy
perplasia associated with chronic cervicitis that may pose a problem in dif
ferential diagnosis from malignant lymphoma. It is a rare entity and only a
bout 20 cases have been reported in the world literature. Two cases of cerv
ical lymphoma-like lesion are described. In both patients, the diagnosis wa
s based on microscopic examination of biopsies taken from the uterine cervi
x. One patient subsequently had a cervical conization that confirmed the di
agnosis of lymphoma-like lesion. Both patients are well, alive and with no
evidence of malignant lymphoma. It is concluded that the diagnosis of lymph
oma-like lesion is based on the well-established characteristic microscopic
features of this lesion. Immunohistochemical staining is usually not helpf
ul in distinguishing this lesion from malignant lymphoma. No specific treat
ment is necessary for this condition. (C) 2001 Elsevier Science Ireland Ltd
. All rights reserved.