S. Sukpanichnant et al., Angiocentric T-cell lymphoma of the pancreas presenting as late-onset diabetes mellitus with diabetic retinopathy, HUMAN PATH, 32(7), 2001, pp. 741-745
Citations number
16
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Pancreatic lymphoma presenting with clinical diabetes mellitus (DM) is rare
. We report angiocentric T-cell lymphoma of the pancreas in a 65-year-old T
hai woman who presented with progressive deterioration of visual acuity of
both eyes. She had diabetic retinopathy (DR) diagnosed only 20 months after
the diagnosis of DM at the age of 63. She later developed erythematous ras
hes, fever, and deterioration of consciousness; she eventually died of shoc
k. A skin biopsy and bone marrow examination revealed angiocentric T-cell l
ymphoma. At autopsy, the pancreas and both eyes were extensively infiltrate
d by lymphoma. Widespread involvement of nearly all organs but superficial
lymphadenopathy was detected. In contrast to other typical cases of long-st
anding DM, only mild atherosclerosis was noted, and no DR was found. To the
best of our knowledge, this is the first case of lymphoma involving the pa
ncreas and both eyes producing clinical DM and DR. HUM PATHOL 32:741-745. C
opyright (C) 2001 by W.B. Saunders Company.