A. Bener et al., Association between blood levels of lead, blood pressure and risk of diabetes and heart disease in workers, INT A OCCUP, 74(5), 2001, pp. 375-378
Citations number
25
Categorie Soggetti
Envirnomentale Medicine & Public Health","Pharmacology & Toxicology
Journal title
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
Background: Previous studies have supported the association between high le
vels of blood lead levels (BLL) and elevated blood pressure. In addition, s
ignificant correlations between BLL and a variety of risk factors for blood
pressure and diabetes mellitus have been well-established. Objective: To e
xamine the relationship between BLL, blood pressure and diabetes as well as
other selected social and biochemical factors, among workers in the United
Arab Emirates (UAE). Methods: This comparative study included 110 industri
al workers (exposed to lead in the workplace) and 110 non-industrial worker
s (not exposed), all were recruited in the city of Al-Ain, Abu-Dhabi Emirat
e, UAE and the groups were evenly matched for age, gender and nationality.
Results: The industrial workers had a significantly higher mean of BLL (med
ian 81 and geometric mean (GM) 62 mug/dl) than did non-industrial workers (
median 11 and GM 13 mug/dl). In the present study, the lead-exposed group a
lso had significantly higher blood lead levels, body-mass index (BMI), syst
olic and diastolic blood pressures., fasting blood glucose and plasma level
s of total cholesterol, lactate dehydrogenase and uric acid than did the no
n-exposed group. Furthermore a significant correlation between BLL and syst
olic blood pressure was observed. Conclusion: The study supports the hypoth
esis of a positive association between lead exposure, high blood pressure a
nd risk of diabetes and heart disease.