Identification of a new imprinted gene, Rian, on mouse chromosome 12 by fluorescent differential display screening

Citation
I. Hatada et al., Identification of a new imprinted gene, Rian, on mouse chromosome 12 by fluorescent differential display screening, J BIOCHEM, 130(2), 2001, pp. 187-190
Citations number
16
Categorie Soggetti
Biochemistry & Biophysics
Journal title
JOURNAL OF BIOCHEMISTRY
ISSN journal
0021924X → ACNP
Volume
130
Issue
2
Year of publication
2001
Pages
187 - 190
Database
ISI
SICI code
0021-924X(200108)130:2<187:IOANIG>2.0.ZU;2-I
Abstract
Systematic screening of differentially expressed genes among androgenetic, parthenogenetic, and normal embryos by means of fluorescent differential di splay revealed five imprinted genes. One of them, named Rian, was expressed exclusively from the maternal allele and was closely linked to an imprinte d gene, Meg3(Gtl2), mapped to the distal end of chromosome 12. The Rian tra nscript did not have any apparent open reading frame, and its transcript wa s exclusively localized to the nucleus.