We describe a 54-year-old male with severe coronary artery disease and cere
brovascular disease including right cerebellar infarction, total occlusion
of the bilateral vertebral arteries, brainstem. ischemia, and right cerebra
l infarction with significant right carotid artery disease. Repeated percut
aneous transluminal coronary angioplasty had been performed, however, unsta
ble angina was developed despite maximal medical treatment. Coronary artery
bypass grafting was successfully undergone with use of propofal, applicati
on of the intraaortic balloon pumping perioperatively, and mad hypothermic
cardiopulmonary bypass with alpha-stat blood gas management. The importance
of preoperative evaluation of the intracranial circulation and management
of cardiopulmonary bypass are discussed.