Serological differentiation of experimentally induced Candida dubliniensisand Candida albicans infections

Using a rabbit model of systemic infection, we show that it is possible to differentiate infections caused by Candida dubliniensis and other Candida s pecies by detecting the antibody response mounted by the infected animals. These results confirm our previous observation in a patient with C. dublini ensis candidemia and suggest that detection of C. dubliniensis-specific ant ibodies is useful in the diagnosis of invasive candidiasis caused by this y east.