Acute renal failure (ARF) occurs in many critically ill patients regar
dless of age. A combination of events often seen in critical care sett
ings, including shock, sepsis, hypoxia, and the use of potentially nep
hrotoxic medications, combine to make ARF an ongoing and important man
agement issue in critical care medicine. Since the events leading to t
he development of ARF differ in infants, children, adults, and the eld
erly, the pathophysiology, clinical features, and treatment modalities
do indeed have remarkable similarities among the different age groups
.