Surgical treatment of prosthetic valve endocarditis with left ventricular-aortic discontinuity: Reconstruction of the left ventricular outflow tract with a xenopericardial conduit

Background and aim of the study: Aortic prosthetic valve endocarditis (PVE) with annular destruction presents a challenge that requires techniques to eradicate the infection and correct the hemodynamic abnormality. Methods: Between July 1, 1996 and March 31, 2000, six patients with native or PVE of the aortic valve and aortic annular destruction underwent surgica l treatment. Of these patients, three (two men, one woman; mean age 71.0 ye ars) had circumferential annular destruction of the aortic annulus, and for med the basis of this study. The microorganisms responsible for the infecti on were Streptococcus spp. in two patients and Staphylococcus aureus in one patient. In addition to aggressive debridement of the infected tissue, rep air was achieved by reconstruction of the left ventricular outflow tract wi th a xenopericardial conduit and fixation of the new prosthetic valve to th e conduit. Results: One patient with ventricular septal perforation, multiple systemic embolism and sepsis died of low cardiac output syndrome soon after surgery Two operative survivors were followed up for 9 and 51 months, with no late deaths. No patient has experienced recurrent infection, pericardial patch aneurysm, or prosthetic valve detachment. Conclusion. These operative procedures provide easy and secure fixation of the pericardial patch to the healthy tissue under excellent operative view, as well as a sturdy structure for the fixation of the new prosthesis, and complete exclusion of the abscess cavity from the blood stream.