Persons with schizophrenia are widely recognized to experience potent feeli
ngs of hopelessness, helplessness, and a fragile sense of well-being. Altho
ugh these subjective experiences have been linked to positive symptoms, lit
tle is known about their relationship to neurocognition. Accordingly, this
study examined the relationship of self-reports of hope, self-efficacy, and
well-being to measures of neurocognition, symptoms, and coping among 49 pe
rsons with schizophrenia or schizoaffective disorder. Results suggest that
poorer executive function, verbal memory, and a greater reliance on escape
avoidance as a coping mechanism predicted significantly higher levels of ho
pe and well being with multiple regressions accounting for 34% and 20% of t
he variance (p < .0001), respectively. Self-efficacy predicted lower levels
of positive symptoms and greater preference for escape avoidance as a copi
ng mechanism with a multiple repression accounting for 9% of the variance (
p < .05). Results may suggest that higher levels of neurocognitive impairme
nt and an avoidant coping style may shield some with schizophrenia from pai
nful subjective experiences. Theoretical and practical implications for reh
abilitation are discussed.