Co-occurence of multiple sclerosis and glioma

The simultaneous occurrence of multiple sclerosis and a primary brain neopl asm is exceptional: only 32 cases have been reported in the literature. We report the case of a 30-year-old woman with multiple sclerosis proven for 1 0 years who developed a grade 11 astrocytoma revealed by MRI. At the pathol ogy examination, there was no cellular continuity with areas of demyelinize d white matter. Unlike the hypothesis put forward in certain publications d escribing this association that argue for an induction link between these t wo entities, our case did not demonstrate any spatial or temporal relations hip suggestive a common cause.