Background: Patients who have experienced severe caustic injury to the gast
rointestinal tract are at high risk of esophageal strictures. Early endosco
py is usually recommended systematically in children after caustic ingestio
n to assess the severity of the initial digestive lesions. The aim of this
study was to determine the predictive value of clinical symptoms and ingest
ed-substance types as markers of severe esophagogastric lesions and to defi
ne indications for endoscopy.
Methods: Ingested-product types, clinical symptoms, endoscopic data and out
come were prospectively recorded in 85 children admitted after accidental c
austic ingestion.
Results: Forty-eight children (57%) had no symptoms; the others presented w
ith vomiting, hematemesis, drooling, respiratory distress, and/or oropharyn
geal lesions. Endoscopy showed no or minimal lesions in 63 cases (74%). Non
e of the children developed digestive sequelae. Severe esophagogastric lesi
ons were present in 22 cases (26%), mostly caused by lye ingestion (14 of 2
2) but also by strong acids (4 of 22); 9 of the 22 children (41%) developed
esophageal stenosis. Vomiting, drooling, and oropharyngeal lesions did not
predict severe endoscopic lesions. Hematemesis, respiratory distress, or p
resence of at least three of the symptoms was associated with severe lesion
s (positive predictive value = 1). The absence of symptoms was always assoc
iated with no or minimal lesions (negative predictive value = 1).
Conclusions: In conclusion, endoscopy is not recommended for children livin
g in developed countries who are asymptomatic after accidental caustic inge
stion.