A new serotype adenovirus isolated from a goat in the United States

A virus (T94-0353) isolated from the small intestine of a 3-week-old kid wi th diarrhea and serous ocular and nasal discharge was identified as an aden ovirus based on morphologic and physicochemical characteristics. Neutraliza tion tests and restriction endonuclease analysis comparing the caprine aden ovirus with the prototype bovine and ovine adenovirus serotypes and a previ ously isolated caprine adenovirus showed that the caprine isolate was antig enically distinct, produced a unique restriction pattern compared with curr ently recognized bovine, caprine, and ovine adenoviruses, and represents a new adenovirus type. The role and significance of naturally acquired adenov irus infection in respiratory and enteric disease in goats has not been est ablished. Isolation of adenovirus from goats with disease coupled with sero epidemiologic and pathogenicity studies will help define the role of the ad enoviruses in disease production.