Defaulting patterns in a provincial leprosy control programme in Northern Mozambique

Cohort-based multidrug therapy (MDT) completion rates are used to assess ad herence to MDT. However this measure gives no information about when during the treatment period defaulting occurs. Two districts in Cabo Delgado prov ince in Northern Mozambique were selected for evaluation of multibacillary patient defaulter data between 1993 and 1997 to examine when patients defau lt during the treatment period. In all, 548 (59.2%) of 926 MB patients comp leted treatment and 378 (40.8%) defaulted between 1993 to 1997. The percent age of defaulters fell steadily from 59.8% in 1993 to 23.2% in 1997. Of the 378 defaulters 57.7% defaulted treatment within 6 months and 83.1% within I year of starting treatment. It was observed that patients tend to default early rather than late in the treatment period and that this pattern is ma intained over time despite a fall in defaulter rates. Patients established early into a treatment routine were more likely to complete treatment. A co mprehensive effort to improve and maintain leprosy control services will pr obably influence adherence more than any single, specific strategy. Shorten ing MDT treatment from 2 years to 1 year is unlikely to affect the defaulte r rate.