SUCCESSFUL BIRTH AFTER INTRAFALLOPIAN TRANSFER OF MICROHATCHED EMBRYOS

Objective: To present a successful transfer of microhatched embryos to the fallopian tubes via microlaparoscopy. Design: Case report. Settin g: Private practice affiliated with a medical university. Patient: A 4 0-year-old woman with primary infertility, mildly elevated baseline FS H levels, and a history of poor ovarian response to ovulation inductio n. Her husband had severe oligoospermia after vasectomy reversal. Inte rvention(s): Late luteal leuprolide acetate to pituitary down-regulati on followed by pure FSH, 300 IU, and hMG, 300 IU, daily for ovulation induction. Transvaginal oocyte retrieval, intracytoplasmic sperm injec tion, assisted embryo hatching, microlaparoscopic intrafallopian ET. M ain Outcome Measure(s): Amniocentesis at the 14th week of gestation re vealed a normal karyotype (46,XX); birth of a normal female infant (37 00 g). Result(s): Establishment of a single, viable intrauterine gesta tion followed by a vaginal delivery at term. Conclusion(s): This case shows the possibility of using assisted-hatched embryos for laparoscop ic intrafallopian tube transfer. (C) 1997 by American Society for Repr oductive Medicine.