Cell genesis in the hypothalamus is associated to the sexual phase of a hermaphrodite teleost

Citation
B. Zikopoulos et al., Cell genesis in the hypothalamus is associated to the sexual phase of a hermaphrodite teleost, NEUROREPORT, 12(11), 2001, pp. 2477-2481
Citations number
25
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NEUROREPORT
ISSN journal
09594965 → ACNP
Volume
12
Issue
11
Year of publication
2001
Pages
2477 - 2481
Database
ISI
SICI code
0959-4965(20010808)12:11<2477:CGITHI>2.0.ZU;2-V
Abstract
The present study aimed to define sex differences in the genesis of hypotha lamic and telencephalic cells in the adult brain of male, female and under sex reversal teleosts (Sparus aurata). Application of 5-bromo-2-deoxyuridin e immunocytochemistry and quantification of the newborn cells using the dis ector method, determined a statistically significant difference in the dors al hypothalamic ventricular area between sexual phases. Female brain exhibi ted a higher number of newborn cells, suggesting that estrogens possibly in fluence higher mitotic activity. In contrast, paraventricular organ and ven tral nucleus of the ventral telencephalon did not show any significant chan ges, while cell proliferation differences in the preoptic area were correla ted with age. The sex-specific cell proliferation pattern in the hypothalam us adds important information on the cellular mechanisms that underlie sex change in a protandrous hermaphrodite teleost. NeuroReport 12:2477-2481 (C) 2001 Lippincott Williams & Wilkins.