Thermodynamic and kinetic studies of oxidation of L-histidine by manganese(VII) in concentrated sulfuric acid medium in the absence and presence of silver(I)

Thermodynamic and kinetic studies and mechanism of manganese{VII) oxidation of L-histidine has been studied both in the absence and presence of silver (I) in aqueous sulfuric acid medium. Various hypotheses for the mechanism o f acid catalysis have been tested and it has been found that rate is relate d to the activity of water in accord with Bunnett's hypothesis. The energy and entropy of activation and frequency factor have been calculated using t he Arrhenius and Eyring plots. Mechanisms in agreement with the observation s ate reported. The experimental rate law for the both uncatalyzed reaction and in the presence of silver was found. The applicability of Burnett's th eory has been tested.