The sensitivity to different relevant parameters of the absorbed fraction o
f alpha particles emitted from the Rn-222 chain in sensitive cells of the t
racheo-bronchial tree have been investigated. The structure of the airway w
all given by ICRP (ICRP66) has been adopted and employed in the present cal
culations. The source thickness (mucous gel and sol + cilia), target layer
thickness and the depth of the sensitive layers have been varied within rea
sonable ranges around the default values recommended by ICRP66. The results
have shown that the depth of the sensitive layers is the most important pa
rameter in calculating the absorbed fraction. In addition, dose conversion
coefficients were calculated and presented along with the absorbed fraction
s.