Investigation of the regioselectivity of alkylation of 3-nitropyridin-2(1H)-ones

Authors
Kislyi, VP Semenov, VV
Citation
Vp. Kislyi et Vv. Semenov, Investigation of the regioselectivity of alkylation of 3-nitropyridin-2(1H)-ones, RUSS CHEM B, 50(3), 2001, pp. 460-463
Citations number
7
Categorie Soggetti
Chemistry
Journal title
RUSSIAN CHEMICAL BULLETIN
ISSN journal
10665285 → ACNP
Volume
50
Issue
3
Year of publication
2001
Pages
460 - 463
Database
ISI
SICI code
1066-5285(200103)50:3<460:IOTROA>2.0.ZU;2-J
Abstract
Alkylation of 3-nitropyridin-2(1H)-ones in the presence of bases affords N- alkylated products and sometimes O-alkylated products. The yields and relat ive amounts of N- and O-alkylated products depend substantially on the size of the substituent at the C(6) atom of pyridone.