Use of methyllithium in metal/halogen exchange; A mild and efficient method for the synthesis of ortho substituted toluenes

Authors
Andrews, IP Kitteringham, J Voyle, M
Citation
Ip. Andrews et al., Use of methyllithium in metal/halogen exchange; A mild and efficient method for the synthesis of ortho substituted toluenes, SYN COMMUN, 31(15), 2001, pp. 2323-2327
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
15
Year of publication
2001
Pages
2323 - 2327
Database
ISI
SICI code
0039-7911(2001)31:15<2323:UOMIME>2.0.ZU;2-4
Abstract
Methyllithium, in the presence of excess methyl iodide, can be used to conv ert suitably substituted aromatic bromides to the corresponding toluenes un der mild conditions and in high yield.