Influence of the reaction conditions in the N-alkylation of acridone-2-carboxylic acids

Authors
Marill, LX Comdom, RFP Hermandez, MM
Citation
Lx. Marill et al., Influence of the reaction conditions in the N-alkylation of acridone-2-carboxylic acids, SYN COMMUN, 31(14), 2001, pp. 2159-2167
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
14
Year of publication
2001
Pages
2159 - 2167
Database
ISI
SICI code
0039-7911(2001)31:14<2159:IOTRCI>2.0.ZU;2-7
Abstract
The synthesis and a study about the influence of the solvent in the alkylat ion reaction of 2-Carboxy-6-chloro-9(10H) acridone (3b) and 2-Carboxy-6-chl oro-7-nitro-9(10H) acridone (3a) was done, obtaining the N-ethyl ester deri vative of the alkylated products. Using the liquid-liquid phase transfer ca talysis only the N-alkylated derivative was obtained in both cases with an improved yield.