Asymmetric auto-inductive aldol reaction by self-assembly of chiral ligands

Authors
De Rosa, M Acocella, MR Soriente, A Scettri, A
Citation
M. De Rosa et al., Asymmetric auto-inductive aldol reaction by self-assembly of chiral ligands, TETRAHEDR-A, 12(10), 2001, pp. 1529-1531
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
10
Year of publication
2001
Pages
1529 - 1531
Database
ISI
SICI code
0957-4166(20010622)12:10<1529:AAARBS>2.0.ZU;2-K
Abstract
The Ti(IV)/(R)-BINOL catalyzed aldol condensation of trimethylsilyloxydiene , deriving from 2,2,6-trimethyl-4H-[1,3]-dioxin-4-one, is shown to proceed through an auto-inductive process with amplification of enantiomeric excess (e.e.). (C) 2001 Elsevier Science Ltd. All rights reserved.