D. Sole et al., Palladium-catalyzed intramolecular coupling of aryl halides and ketone enolates: Synthesis of hexahydro-2,6-methano-1-benzazocines, ADV SYNTH C, 343(5), 2001, pp. 439-442
The palladium-catalyzed intramolecular coupling of 2-haloanilines and keton
e enolates is a useful methodology for the synthesis of hexahydro-2,6-metha
no-1-benzazocine derivatives. A study about the reaction conditions of the
process is reported.