Investigation of salicylate interference on anion selective electrodes

Several types of ion-selective membranes were tested to decrease the salicy late interference in clinical measurements of chloride. The study included electrodes with methyldode-cylammonium salt and membrane matrices of poly(v inyl chloride) (PVC), silicone rubber (SR) and cellulose triacetate (CTA). The first two membranes were modified by the ultrafiltration (UF) and nanof iltration (NF) membranes, respectively, the cellulose triacetate membrane w as modified by alkaline hydrolysis. The most significant and useful decreas e by one and half order of magnitude of log K-Cl,Sal(pot) was observed for the silicone rubber membrane with additional nanofilter membrane.