Fine-needle aspiration biopsy features in a case of giant cell fibroblastoma of the chest wall

Giant cell fibroblastoma is an unusual tumor of childhood, primarily occurr ing in the superficial soft tissues. We describe the fine-needle aspiration biopsy features of a case of giant cell fibroblastoma of the chest wall in a 3-year-old child. The aspirates comprised bland spindle to oval cells en trapped in a metachromatic matrix, accompanied by rare multinucleated giant cells with wreathlike nuclei. Although we were unable to render a definiti ve diagnosis on fine-needle aspiration biopsy, surgical resection of the ma ss established the diagnosis of giant cell fibroblastoma. We review the dis tinctive cytologic features of some common soft tissue tumors arising in th is age group that may give rise to a diagnostic conundrum on fine-needle as piration biopsy.