Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase: Solid-phase synthesis of ornithine analogues

Authors
Dankwardt, SM Martin, RL Chan, CS Van Wart, HE Walker, KAM Delaet, NG Robinson, LA
Citation
Sm. Dankwardt et al., Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase: Solid-phase synthesis of ornithine analogues, BIOORG MED, 11(16), 2001, pp. 2085-2088
Citations number
9
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
16
Year of publication
2001
Pages
2085 - 2088
Database
ISI
SICI code
0960-894X(20010820)11:16<2085:AADSHA>2.0.ZU;2-C
Abstract
A discussion of the solid-phase synthesis of ornithine derived sulfonamide hydroxamic acids is illustrated. These analogues are shown to be potent, no n-peptide inhibitors of procollagen C-proteinase (PCP). (C) 2001 Elsevier S cience Ltd. All rights reserved.