Sorting of preproteins into mitochondria

Authors
Krimmer, T Geissler, A Pfanner, N Rassow, J
Citation
T. Krimmer et al., Sorting of preproteins into mitochondria, CHEMBIOCHEM, 2(7-8), 2001, pp. 505
Citations number
145
Categorie Soggetti
Chemistry & Analysis
Journal title
CHEMBIOCHEM
ISSN journal
14394227 → ACNP
Volume
2
Issue
7-8
Year of publication
2001
Database
ISI
SICI code
1439-4227(20010803)2:7-8<505:SOPIM>2.0.ZU;2-B
Abstract
The proteins of mitochondria are provided by two different genetic systems. Following synthesis in the mitochondrial matrix or in the cytosol, they ar e specifically sorted into four mitochondrial compartments. The machineries , including the TOM complex (see picture), that direct the newly synthesize d preproteins to their functional locations have been identified and are no w studied in their molecular details.