One of the most common clinical problems for endocrinologists is the evalua
tion of thyroid nodules. Radionuclide scans and thyroid ultrasonography, tr
aditionally used to distinguish malignant from benign nodules, are costly a
nd provide nonspecific results. Currently, authors of clinical practice gui
delines recommend fine-needle aspiration (FNA) cytology as the best initial
test for evaluating thyroid nodules. This paper reviews the practice patte
rns of thyroid specialists and primary care providers at the Gundersen Luth
eran Medical Center and summarizes the pattern of thyroid nodule evaluation
published by other endocrinologists. The results indicate that FNA cytolog
y was widely used at our institution by both thyroid specialists and primar
y care providers. Since the introduction of FNA cytology, the use of radio.
nuclide scanning has decreased from 90% to 12% and the use of thyroid ultr
asonography from 30% to 10%. Although the frequency of thyroid surgery fell
, the detection of thyroid cancer in operative specimens increased from 16%
to 43%, whereas the cost of removing, a thyroid carcinoma decreased from $
64,000 to $25,000. Primary care physicians used imaging studies modestly an
d generated $106 per patient in unnecessary costs. Thyroid specialists occa
sionally used radionuclide scanning but did not use thyroid ultrasonography
; they generated $41 per patient in unnecessary costs. Review of the practi
ce patterns of U.S. endocrinologists indicate that they have widely accepte
d FNA cytology and used fewer thyroid tests than primary care providers and
European endocrinologists for evaluating thyroid nodules. However, they ma
y be increasing the use of thyroid ultrasonography and order radioiodine up
take tests and in vitro studies unnecessarily. Avoiding unnecessary costs i
ncurred in the evaluation of 275,000 thyroid nodules detected annually coul
d save millions of dollars.