Objective: The composite mechanical valve conduit has been most commonly us
ed for patients who require combined aortic valve, root,and ascending aorta
replacement, but is limited, especially in the elderly, because of the nee
d for long-term anticoagulation. We report the first consecutive series of
patients in whom a composite stentless valve with graft extension, which do
es not require long-term anticoagulation, was performed. Methods: Between A
pril 1998 and July 2000, eight patients with severe aortic root and ascendi
ng aortic pathology underwent a combined aortic valve, root, and ascending
aorta replacement with a Freestyle((R)) stentless porcine valve with a Hema
shield((R)) graft extension. Mean age was 74 (range 56-82), three were male
s. Concomitant procedures included coronary artery bypass graft (CABG) alon
e (n = 2), mitral valve replacement with atrial septal defect repair (n = 1
) and CABG with septal myomectomy (n = 1). Results: Operative mortality was
zero. Median aortic cross-clamp and cardiopulmonary bypass times were 150
and 203 min, respectively. Two patients returned to the operating room for
bleeding. Median blood transfusions and hospital length of stay were 4 unit
s and 11 days, respectively. Conclusions: The composite stentless valve wit
h graft extension is a reasonable alternative to a mechanical valve conduit
for patients who require a combined aortic valve, root, and ascending aort
a replacement, in whom anticoagulation is not desirable or contra-indicated
. (C) 2001 Elsevier Science B.V. All rights reserved.