Reproductive outcome after laparoscopic instillation of hyperosmolar glucose into unruptured tubal pregnancies

Objective: To determine intrauterine and ectopic pregnancy rates after loca l instillation of 50% glucose into unruptured tubal pregnancies. Design: Retrospective cohort of 183 patients, who were observed for 16 to 1 08 months (median, 64 months). Setting: University hospital. Patient(s): One hundred eighty-three women who underwent laparoscopic insti llation of hyperosmolar glucose for unruptured tubal pregnancies. Intervention(s): Completion of questionnaires. Main Outcome Measure(s): Preganancy rate, tubal recurrence rate. Result(s): A total of 124 women returned the questionnaire and had a desire for spontaneous conception. The conception rate and the intrauterine pregn ancy rate were 79% and 73%, respectively. Seventy percent of all women with desire for spontaneous conception had Live births. The rate of subsequent ectopic pregnancies was 12%. Tubal patency of the treated tube was demonstr ated in 69% of 39 women at hysterosalpingography. Conclusion(s): The long-term prognosis for conception after laparoscopic in stillation of hyperosmolar glucose for unruptured tubal pregnancy is favora ble and comparable to that of other conservative treatments. (C) 2001 by Am erican Society for Reproductive Medicine.