We report two identical male twins who suffered from superior mesenteric ar
tery (SMA) syndrome. A 28-year-old man was admitted for investigation of po
stprandial nausea and vomiting. Upper gastrointestinal examination revealed
a dilated proximal duodenum with an abrupt vertical cutoff of barium flow
in the third portion of the duodenum, establishing the diagnosis of SMA syn
drome. One year later, his twin brother also presented similar symptoms and
was radiologically diagnosed as SMA syndrome. The twin brothers did not re
spond adequately to conservative therapy and underwent duodenojejunostomy.
This is the first report of SMA syndrome in identical twins.