Painless thyroiditis induced by the cessation of betamethasone

We describe the first reported case of painless thyroiditis induced by an a brupt cessation of betamethasone. A 53-year-old woman experienced transient thyrotoxicosis after the abrupt cessation of celestamine, a mixture of bet amethasone and chlorpheniramine. Since neither TSH receptor- nor thyroid st imulating-antibodies were negative, and thyroid scintigram did not show the thyroid gland, she was diagnosed as having painless thyroiditis. Fourteen months after the onset of thyrotoxicosis, serum TSH was detectable without hypothyroidism. We speculate that reduction in betamethasone may be one of the triggers of painless thyroiditis.