E. Machida et al., Pulmonary epithelioid hemangioendothelioma coexistent with pulmonary metastasis of thyroid cancer, INTERN MED, 40(8), 2001, pp. 772-774
We report a 45-year-old man with epithelioid hemangioendothelioma (EH) and
simultaneous pulmonary metastasis of thyroid cancer in his lung. Thyroid ca
ncer, and multiple small nodules in both lungs were noted. He underwent tot
al thyroidectomy followed by radiotherapy with I-131. However, I-131 scinti
graphy showed poor uptake of radionuclide in the nodules, and the size of t
he nodules remained unchanged. The diagnostic thoracoscopic biopsy showed t
wo types of nodules, some were positive for thyroglobulin and cytokeratin,
and others were reactive for factor VIII. The former nodules were diagnosed
as pulmonary metastases of thyroid cancer, and the latter EH.